Diseases

Striatonigral Degeneration

A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)

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Synonyms

6 entry terms
  • Striatonigral Atrophy
  • Atrophies, Striatonigral
  • Atrophy, Striatonigral
  • Degeneration, Striatonigral
  • Striatonigral Atrophies
  • Striatonigral Degenerations

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Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2000; use MULTIPLE SYSTEM ATROPHY 1998-1999

MeSH Record

Previous Indexing

  • Multiple System Atrophy (1998-1999)
  • Parkinson Disease (1970-1993)
  • Substantia Nigra (1970-1999)

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AMA Style

References

  1. National Library of Medicine. Striatonigral Degeneration. Medical Subject Headings (MeSH). 2026. Unique ID D020955. http://id.nlm.nih.gov/mesh/2026/D020955
  2. Striatonigral Degeneration. In: Wikidata. https://www.wikidata.org/wiki/Q9392705