Phenomena and Processes

Structure-Activity Relationship

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • Relationship, Structure-Activity
  • Relationships, Structure-Activity
  • Structure Activity Relationship
  • Structure-Activity Relationships

MeSH Record

Indexing Annotation

usually NIM

MeSH Record

History Note

72

MeSH Hierarchy

Tree Numbers

  1. G02.111.830w
  2. G07.690.773.997w

AMA Style

References

  1. National Library of Medicine. Structure-Activity Relationship. Medical Subject Headings (MeSH). 2026. Unique ID D013329. http://id.nlm.nih.gov/mesh/2026/D013329
  2. Structure-Activity Relationship. In: Wikipedia. https://en.wikipedia.org/wiki/Structure%E2%80%93activity_relationship
  3. Structure-Activity Relationship. In: Wikidata. https://www.wikidata.org/wiki/Q1772003