Structured Summary
Abstract
ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).
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Classification
Broader headings
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Synonyms
6 entry terms
- ABCB11 Protein
- ATP Binding Cassette Subfamily B Member 11
- ATP Binding Cassette Transporter, Sub-Family B, Member 11
- ATP Binding Cassette Transporter, Subfamily B, Member 11
- BSEP Protein
- Bile Salt Export Pump
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2019 (2018)
MeSH Record
Previous Indexing
- ATP-Binding Cassette Transporters (1995-2017)
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AMA Style
References
- National Library of Medicine. Subfamily B Member 11 ATP Binding Cassette Transporter. Medical Subject Headings (MeSH). 2026. Unique ID D000074020. http://id.nlm.nih.gov/mesh/2026/D000074020
- Subfamily B Member 11 ATP Binding Cassette Transporter. In: Wikidata. https://www.wikidata.org/wiki/Q4650061