Chemicals and Drugs

Subfamily B Member 2 ATP Binding Cassette Transporter

An ATP-binding cassette, sub-family B protein (ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B) that functions in the transport of ANTIGENS from the CYTOPLASM to the ENDOPLASMIC RETICULUM for association with HISTOCOMPATIBILITY ANTIGENS CLASS I peptides. It also acts as a molecular scaffold for the final stage of MHC class I PROTEIN FOLDING.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An ATP-binding cassette, sub-family B protein (ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B) that functions in the transport of ANTIGENS from the CYTOPLASM to the ENDOPLASMIC RETICULUM for association with HISTOCOMPATIBILITY ANTIGENS CLASS I peptides. It also acts as a molecular scaffold for the final stage of MHC class I PROTEIN FOLDING.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

17 entry terms
  • ABCB2 Protein
  • ATP Binding Cassette Transporter, Sub-Family B, Member 2
  • ATP Binding Cassette Transporter, Subfamily B, Member 2
  • ATP-Binding Cassette Sub-Family B Member 2
  • Antigen Peptide Transporter-1
  • Peptide Transporter PSF1
  • Peptide Transporter TAP1
  • RING4 Protein
  • Really Interesting New Gene 4 Protein
  • TAP-1 Protein
  • TAP1 Protein
  • Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR-TAP)
  • ATP Binding Cassette Sub Family B Member 2
  • Antigen Peptide Transporter 1
  • PSF1, Peptide Transporter
  • TAP 1 Protein
  • TAP1, Peptide Transporter

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2019 (2017)

MeSH Record

Previous Indexing

  • ATP-Binding Cassette Transporters (1994-2016)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.020w.400.305
  2. D12.776w.157w.530w.100w.075.250
  3. D12.776w.157w.530w.450w.074.500w.500.250.250
  4. D12.776w.395w.550w.020w.400.305
  5. D12.776w.543w.550w.192w.400.305
  6. D12.776w.543w.585w.100w.200.250
  7. D12.776w.543w.585w.450w.074.500w.500.250.250

AMA Style

References

  1. National Library of Medicine. Subfamily B Member 2 ATP Binding Cassette Transporter. Medical Subject Headings (MeSH). 2026. Unique ID D000071181. http://id.nlm.nih.gov/mesh/2026/D000071181
  2. Subfamily B Member 2 ATP Binding Cassette Transporter. In: Wikidata. https://www.wikidata.org/wiki/Q24771245