Chemicals and Drugs

Subfamily G ATP Binding Cassette Transporter

A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • ABCG Proteins
  • ABCG Transporter
  • ABCG Transporters
  • ATP Binding Cassette Transporter, Sub-Family G
  • ATP Binding Cassette Transporter, Subfamily G
  • ATP Binding Cassette Transporter, Sub Family G
  • Transporter, ABCG

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2019 (2017)

MeSH Record

Previous Indexing

  • ATP-Binding Cassette Transporters (2001-2016)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.020w.457
  2. D12.776w.157w.530w.100w.228
  3. D12.776w.395w.550w.020w.457
  4. D12.776w.543w.550w.192w.457
  5. D12.776w.543w.585w.100w.228

AMA Style

References

  1. National Library of Medicine. Subfamily G ATP Binding Cassette Transporter. Medical Subject Headings (MeSH). 2026. Unique ID D000070996. http://id.nlm.nih.gov/mesh/2026/D000070996
  2. Subfamily G ATP Binding Cassette Transporter. In: Wikidata. https://www.wikidata.org/wiki/Q77920762