Chemicals and Drugs

Subtilisin

A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

SUBTILISINS is also available

MeSH Record

History Note

2000

MeSH Record

Previous Indexing

  • Endopeptidases (1966-1972)
  • Subtilisins (1973-1999)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.300w.760.787w.805
  2. D08.811w.277w.656w.959w.350.787w.805

AMA Style

References

  1. National Library of Medicine. Subtilisin. Medical Subject Headings (MeSH). 2026. Unique ID D020860. http://id.nlm.nih.gov/mesh/2026/D020860
  2. Subtilisin. In: Wikidata. https://www.wikidata.org/wiki/Q423655