Chemicals and Drugs

Superoxide Dismutase-1

A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Cu-Zn Superoxide Dismutase
  • Cuprozinc Superoxide Dismutase
  • SOD-1 Protein
  • SOD1 Protein
  • Superoxide Dismutase 1
  • Cu Zn Superoxide Dismutase
  • SOD 1 Protein
  • Superoxide Dismutase, Cu-Zn
  • Superoxide Dismutase, Cuprozinc

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1998); for CU-ZN SUPEROXIDE DISMUTASE, use SUPEROXIDE DISMUTASE 1983-2016

MeSH Hierarchy

Tree Number

  1. D08.811w.682w.881w.500

AMA Style

References

  1. National Library of Medicine. Superoxide Dismutase-1. Medical Subject Headings (MeSH). 2026. Unique ID D000072105. http://id.nlm.nih.gov/mesh/2026/D000072105
  2. Superoxide Dismutase-1. In: Wikidata. https://www.wikidata.org/wiki/Q2041084