Chemicals and Drugs

Synaptotagmin II

A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Synaptotagmin 2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1991)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.125w.825w.500
  2. D12.776w.543w.990w.850w.500

AMA Style

References

  1. National Library of Medicine. Synaptotagmin II. Medical Subject Headings (MeSH). 2026. Unique ID D050861. http://id.nlm.nih.gov/mesh/2026/D050861
  2. Synaptotagmin II. In: Wikidata. https://www.wikidata.org/wiki/Q21126482