Anatomy

THP-1 Cells

A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

9 entry terms
  • THP-1 Cell Line
  • Cell Line, THP-1
  • Cell Lines, THP-1
  • Cell, THP-1
  • Cells, THP-1
  • THP 1 Cell Line
  • THP 1 Cells
  • THP-1 Cell
  • THP-1 Cell Lines

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

almost always NIM with no subheadings; check HUMAN; do not routinely add LEUKEMIA, MONOCYTIC, ACUTE

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Cell Line (1986-2017)
  • Macrophages (1986-2017)
  • Monocytes (1988-2017)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. THP-1 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D000074084. http://id.nlm.nih.gov/mesh/2026/D000074084
  2. THP-1 Cells. In: Wikipedia. https://en.wikipedia.org/wiki/THP-1_cell_line
  3. THP-1 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q7670282