Chemicals and Drugs

TNF Receptor-Associated Factor 4

A widely expressed member of the TNF receptor-associated family that may play a role in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor 4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A widely expressed member of the TNF receptor-associated family that may play a role in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor 4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B.

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MeSH Record

Synonyms

6 entry terms
  • Cysteine-Rich Domain Associated with RING and TRAF Domains Protein 1
  • TNF Receptor-Associated Protein 4
  • TRAF4
  • Cysteine Rich Domain Associated with RING and TRAF Domains Protein 1
  • TNF Receptor Associated Factor 4
  • TNF Receptor Associated Protein 4

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1995)

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AMA Style

References

  1. National Library of Medicine. TNF Receptor-Associated Factor 4. Medical Subject Headings (MeSH). 2026. Unique ID D053449. http://id.nlm.nih.gov/mesh/2026/D053449
  2. TNF Receptor-Associated Factor 4. In: Wikidata. https://www.wikidata.org/wiki/Q24769610