Structured Summary
Abstract
A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION.
Chemical Identity
Chemical Information
- Molecular Formula
- C22H19N3O4
- Molecular Weight
- 389.4 g/mol
- CAS Registry No.
- 171596-29-5
- IUPAC Name
- (2R,8R)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
- InChIKey
- WOXKDUGGOYFFRN-IIBYNOLFSA-N
- SMILES
- CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
- MeSH Unique ID
- D000068581
- Source
- PubChem CID 110635
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
See Also
MeSH Record
Synonyms
5 entry terms
- Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3- benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-
- Cialis
- IC 351
- IC-351
- IC351
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2016 (2001)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Tadalafil. Medical Subject Headings (MeSH). 2026. Unique ID D000068581. http://id.nlm.nih.gov/mesh/2026/D000068581
- Tadalafil. In: Wikipedia. https://en.wikipedia.org/wiki/Tadalafil
- Tadalafil. In: Wikidata. https://www.wikidata.org/wiki/Q424156
- Tadalafil. In: PubChem Compound. CID 110635. https://pubchem.ncbi.nlm.nih.gov/compound/110635