Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Tandem Mass Spectrometry

A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Mass Spectrometry-Mass Spectrometry
  • Mass Spectrometry Mass Spectrometry
  • Mass Spectrometry, Tandem

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

History Note

2007

MeSH Record

Previous Indexing

  • Spectrum Analysis, Mass or specifics (1981-2006)

MeSH Hierarchy

Tree Number

  1. E05.196w.566w.880w

AMA Style

References

  1. National Library of Medicine. Tandem Mass Spectrometry. Medical Subject Headings (MeSH). 2026. Unique ID D053719. http://id.nlm.nih.gov/mesh/2026/D053719
  2. Tandem Mass Spectrometry. In: Wikipedia. https://en.wikipedia.org/wiki/Tandem_mass_spectrometry
  3. Tandem Mass Spectrometry. In: Wikidata. https://www.wikidata.org/wiki/Q874296