Structured Summary
Abstract
A thymidine derivative and antiviral agent that inhibits DNA synthesis by HEPATITIS B VIRUS and is used for the treatment of CHRONIC HEPATITIS B.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H14N2O5
- Molecular Weight
- 242.23 g/mol
- CAS Registry No.
- 3424-98-4
- IUPAC Name
- 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
- InChIKey
- IQFYYKKMVGJFEH-CSMHCCOUSA-N
- SMILES
- CC1=CN(C(=O)NC1=O)[C@@H]2C[C@H]([C@@H](O2)CO)O
- MeSH Unique ID
- D000077712
- Source
- PubChem CID 159269
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- 1-(2-Deoxy-beta-L-erythropentafuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
- Telbivudin
- beta-L-2'-Deoxythymidine
- beta L 2' Deoxythymidine
- Tyzeka
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (2004)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Telbivudine. Medical Subject Headings (MeSH). 2026. Unique ID D000077712. http://id.nlm.nih.gov/mesh/2026/D000077712
- Telbivudine. In: Wikipedia. https://en.wikipedia.org/wiki/Telbivudine
- Telbivudine. In: Wikidata. https://www.wikidata.org/wiki/Q413621
- Telbivudine. In: PubChem Compound. CID 159269. https://pubchem.ncbi.nlm.nih.gov/compound/159269