Anatomy

Telomeric Repeat Binding Protein 1

A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • TERF1 Protein
  • TRF1 Protein
  • TTAGGG Repeat Binding Factor 1
  • TERF1 Proteins
  • TRF1 Proteins
  • PIN2 Protein
  • PIN2 Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003; for TRF1 PROTEIN use TELOMERE-BINDING PROTEINS (NM) 1997-2002;

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1997-2002)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Telomeric Repeat Binding Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D035321. http://id.nlm.nih.gov/mesh/2026/D035321
  2. Telomeric Repeat Binding Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q21130708