Structured Summary
Abstract
A dacarbazine derivative that is used as an alkylating antineoplastic agent for the treatment of MALIGNANT GLIOMA and MALIGNANT MELANOMA.
Chemical Identity
Chemical Information
- Molecular Formula
- C6H6N6O2
- Molecular Weight
- 194.15 g/mol
- CAS Registry No.
- 85622-93-1
- IUPAC Name
- 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
- InChIKey
- BPEGJWRSRHCHSN-UHFFFAOYSA-N
- SMILES
- CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
- MeSH Unique ID
- D000077204
- Source
- PubChem CID 5394
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
17 entry terms
- 8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one
- Methazolastone
- CCRG 81045
- CCRG-81045
- M&B 39831
- M&B-39831
- NSC 362856
- NSC-362856
- TMZ-Bioshuttle
- TMZA-HE
- Temodal
- Temodar
- Temozolomide Hexyl Ester
- CCRG81045
- M&B39831
- NSC362856
- TMZ Bioshuttle
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1985)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Temozolomide. Medical Subject Headings (MeSH). 2026. Unique ID D000077204. http://id.nlm.nih.gov/mesh/2026/D000077204
- Temozolomide. In: Wikipedia. https://en.wikipedia.org/wiki/Temozolomide
- Temozolomide. In: Wikidata. https://www.wikidata.org/wiki/Q425088
- Temozolomide. In: PubChem Compound. CID 5394. https://pubchem.ncbi.nlm.nih.gov/compound/5394