Structured Summary
Abstract
3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H15NO3
- Molecular Weight
- 197.23 g/mol
- IUPAC Name
- (5S)-3-acetyl-5-[(2S)-butan-2-yl]pyrrolidine-2,4-dione
- InChIKey
- KLBSRSYHIIAQTG-PZICIZFRSA-N
- SMILES
- CC[C@H](C)[C@H]1C(=O)C(C(=O)N1)C(=O)C
- MeSH Unique ID
- D013720
- Source
- PubChem CID 441580
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Acid, Tenuazonic
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
an antineoplastic antibiotic
MeSH Record
History Note
91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
MeSH Record
Previous Indexing
- Pyrrolidinones (1971-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Tenuazonic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D013720. http://id.nlm.nih.gov/mesh/2026/D013720
- Tenuazonic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q27108395
- Tenuazonic Acid. In: PubChem Compound. CID 441580. https://pubchem.ncbi.nlm.nih.gov/compound/441580