Chemicals and Drugs

Ternary Complex Factors

A subclass of c-ets proto-oncogene proteins that were first described by their property of binding to DNA when associated with other regulatory proteins such as SERUM RESPONSE FACTOR. They contain an amino-terminal ets domain that binds to DNA along with centrally located SERUM RESPONSE FACTOR interacting domain, and carboxy-terminal map kinase activation domains. They play an important role in transcriptional regulation by INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subclass of c-ets proto-oncogene proteins that were first described by their property of binding to DNA when associated with other regulatory proteins such as SERUM RESPONSE FACTOR. They contain an amino-terminal ets domain that binds to DNA along with centrally located SERUM RESPONSE FACTOR interacting domain, and carboxy-terminal map kinase activation domains. They play an important role in transcriptional regulation by INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.

MeSH Record

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MeSH Record

Synonyms

4 entry terms
  • Ternary Complex Proteins
  • Ternary Complex Transcription Factors
  • Complex Factors, Ternary
  • Complex Proteins, Ternary

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.665w.600
  2. D12.776w.624.664.700.175w.600
  3. D12.776w.930w.720w.600

AMA Style

References

  1. National Library of Medicine. Ternary Complex Factors. Medical Subject Headings (MeSH). 2026. Unique ID D050801. http://id.nlm.nih.gov/mesh/2026/D050801
  2. Ternary Complex Factors. In: Wikidata. https://www.wikidata.org/wiki/Q78447219