Chemicals and Drugs

Testosterone

A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

Chemical Identity

Chemical Information

Molecular Formula
C19H28O2
Molecular Weight
288.4 g/mol
CAS Registry No.
58-22-0
IUPAC Name
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKey
MUMGGOZAMZWBJJ-DYKIIFRCSA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)CC[C@]34C
MeSH Unique ID
D013739
Source
PubChem CID 6013

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • 17-beta-Hydroxy-4-Androsten-3-one
  • 17 beta Hydroxy 4 Androsten 3 one
  • 17-beta-Hydroxy-8 alpha-4-Androsten-3-one
  • 8-Isotestosterone
  • AndroGel
  • Androderm
  • Andropatch
  • Androtop
  • Histerone
  • Sterotate
  • Sustanon
  • Testim
  • Testoderm
  • Testolin
  • Testopel
  • Testosterone Sulfate
  • 17 beta Hydroxy 8 alpha 4 Androsten 3 one
  • 8 Isotestosterone

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

TESTOSTERONE PROPIONATE is also available

MeSH Record

History Note

1963; for SUSTANON use TESTOSTERONE (NM) 1976-2003; /therapeutic use was TESTOSTERONE, THERAPEUTIC 1965

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.054.079.429.824w
  2. D06.472w.334.851w.968.984w

MeSH Record

NLM Classification

WJ 875

AMA Style

References

  1. National Library of Medicine. Testosterone. Medical Subject Headings (MeSH). 2026. Unique ID D013739. http://id.nlm.nih.gov/mesh/2026/D013739
  2. Testosterone. In: Wikipedia. https://en.wikipedia.org/wiki/Testosterone
  3. Testosterone. In: Wikidata. https://www.wikidata.org/wiki/Q1318776
  4. Testosterone. In: PubChem Compound. CID 6013. https://pubchem.ncbi.nlm.nih.gov/compound/6013