Diseases

Tetanus

A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.

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Synonyms

4 entry terms
  • Clostridium tetani Infection
  • Clostridium tetani Infections
  • Infection, Clostridium tetani
  • Infections, Clostridium tetani

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Aspects Covered

36 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, transmission, urine, veterinary, virology.

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Indexing Annotation

caused by Clostridium tetani; do not confuse with TETANY; do not use for tonic spasm of muscle ( = SPASM) or for tetanic contraction ( = MUSCLE CONTRACTION)

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References

  1. National Library of Medicine. Tetanus. Medical Subject Headings (MeSH). 2026. Unique ID D013742. http://id.nlm.nih.gov/mesh/2026/D013742
  2. Tetanus. In: Wikipedia. https://en.wikipedia.org/wiki/Tetanus
  3. Tetanus. In: Wikidata. https://www.wikidata.org/wiki/Q47790