Chemicals and Drugs

Tetragastrin

L-Tryptophyl-L-methionyl-L-aspartyl-L-phenylalaninamide. The C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

L-Tryptophyl-L-methionyl-L-aspartyl-L-phenylalaninamide. The C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin.

Chemical Identity

Chemical Information

Molecular Formula
C29H36N6O6S
Molecular Weight
596.7 g/mol
CAS Registry No.
1947-37-1
IUPAC Name
(3S)-3-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
InChIKey
RGYLYUZOGHTBRF-BIHRQFPBSA-N
SMILES
CSCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N
MeSH Unique ID
D013758
Source
PubChem CID 446569

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

13 entry terms
  • AOC-Tetragastrin
  • AOC-Tetrapeptide
  • CCK (30-33)
  • CCK-4
  • CKK-4
  • Cholecystokinin (30-33)
  • Cholecystokinin 4
  • Cholecystokinin-Tetrapeptide
  • Gastrin Tetrapeptide
  • AOC Tetragastrin
  • AOC Tetrapeptide
  • Cholecystokinin Tetrapeptide
  • Tetrapeptide, Gastrin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

"smallest peptide fragment of gastrin"

MeSH Record

History Note

91(79); was see under GASTRINS 1979-90

MeSH Record

Previous Indexing

  • Gastrins (1966-1978)
  • Oligopeptides (1973-1978)
  • Peptides (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.317w.413.800w
  2. D12.644w.456w.830w

AMA Style

References

  1. National Library of Medicine. Tetragastrin. Medical Subject Headings (MeSH). 2026. Unique ID D013758. http://id.nlm.nih.gov/mesh/2026/D013758
  2. Tetragastrin. In: Wikipedia. https://en.wikipedia.org/wiki/CCK-4
  3. Tetragastrin. In: Wikidata. https://www.wikidata.org/wiki/Q4456650
  4. Tetragastrin. In: PubChem Compound. CID 446569. https://pubchem.ncbi.nlm.nih.gov/compound/446569