Chemicals and Drugs

Theophylline

A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.

Chemical Identity

Chemical Information

Molecular Formula
C7H8N4O2
Molecular Weight
180.16 g/mol
CAS Registry No.
58-55-9
IUPAC Name
1,3-dimethyl-7H-purine-2,6-dione
InChIKey
ZFXYFBGIUFBOJW-UHFFFAOYSA-N
SMILES
CN1C2=C(C(=O)N(C1=O)C)NC=N2
MeSH Unique ID
D013806
Source
PubChem CID 2153

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

61 entry terms
  • 1,3-Dimethylxanthine
  • 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
  • 1,3 Dimethylxanthine
  • Accurbron
  • Aerobin
  • Aerolate
  • Afonilum Retard
  • Aquaphyllin
  • Armophylline
  • Bronchoparat
  • Bronkodyl
  • Constant-T
  • Elixophyllin
  • Euphylong
  • Glycine Theophyllinate
  • Lodrane
  • Monospan
  • Nuelin
  • Nuelin S.A.
  • Quibron T-SR
  • Slo-Phyllin
  • Somophyllin-T
  • Sustaire
  • Synophylate
  • Theo Von Ct
  • Theo-24
  • Theo-Dur
  • Theobid
  • Theocin
  • Theoconfin Continuous
  • Theodur
  • Theolair
  • Theolix
  • Theon
  • Theonite
  • Theopek
  • Theophylline Anhydrous
  • Theophylline Sodium Glycinate
  • Theospan
  • Theostat
  • Theovent
  • Uniphyl
  • Uniphyllin
  • Uniphylline
  • Anhydrous, Theophylline
  • Constant T
  • ConstantT
  • Ct, Theo Von
  • Glycinate, Theophylline Sodium
  • Quibron T SR
  • Quibron TSR
  • Slo Phyllin
  • SloPhyllin
  • Sodium Glycinate, Theophylline
  • Somophyllin T
  • SomophyllinT
  • Theo 24
  • Theo Dur
  • Theo24
  • Theophyllinate, Glycine
  • Von Ct, Theo

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 107

AMA Style

References

  1. National Library of Medicine. Theophylline. Medical Subject Headings (MeSH). 2026. Unique ID D013806. http://id.nlm.nih.gov/mesh/2026/D013806
  2. Theophylline. In: Wikipedia. https://en.wikipedia.org/wiki/Theophylline
  3. Theophylline. In: Wikidata. https://www.wikidata.org/wiki/Q407308
  4. Theophylline. In: PubChem Compound. CID 2153. https://pubchem.ncbi.nlm.nih.gov/compound/2153