Chemicals and Drugs

Thioguanine

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.

Chemical Identity

Chemical Information

Molecular Formula
C5H5N5S
Molecular Weight
167.19 g/mol
CAS Registry No.
154-42-7
IUPAC Name
2-amino-3,7-dihydropurine-6-thione
InChIKey
WYWHKKSPHMUBEB-UHFFFAOYSA-N
SMILES
C1=NC2=C(N1)C(=S)N=C(N2)N
MeSH Unique ID
D013866
Source
PubChem CID 2723601

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • 2-Amino-6-Purinethiol
  • 6-Thioguanine
  • Tioguanine
  • 2 Amino 6 Purinethiol
  • 6 Thioguanine
  • Lanvis
  • Tabloid
  • Thioguanin-GSK
  • Thioguanine Anhydrous
  • Thioguanine Hemihydrate
  • Thioguanine Monosodium Salt
  • Thioguanine Tabloid
  • Tioguanina Wellcome
  • Anhydrous, Thioguanine
  • Thioguanin GSK
  • ThioguaninGSK

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1966(1964)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Thioguanine. Medical Subject Headings (MeSH). 2026. Unique ID D013866. http://id.nlm.nih.gov/mesh/2026/D013866
  2. Thioguanine. In: Wikipedia. https://en.wikipedia.org/wiki/Tioguanine
  3. Thioguanine. In: Wikidata. https://www.wikidata.org/wiki/Q385347
  4. Thioguanine. In: PubChem Compound. CID 2723601. https://pubchem.ncbi.nlm.nih.gov/compound/2723601