Diseases

Thrombasthenia

A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).

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Classification

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MeSH Record

Synonyms

15 entry terms
  • Deficiency of GP 2b 3a Complex
  • GP IIb-IIIa Complex, Deficiency Of
  • Glanzmann Thrombasthenia
  • Glanzmann Thrombasthenia, Type A
  • Glycoprotein Complex IIb-IIIa, Deficiency Of
  • Platelet Fibrinogen Receptor, Deficiency of
  • Platelet Glycoprotein 2b-3a Deficiency
  • Platelet Glycoprotein IIb-IIIa Deficiency
  • Thrombasthenia of Glanzmann and Naegeli
  • GP IIb IIIa Complex, Deficiency Of
  • Glycoprotein Complex IIb IIIa, Deficiency Of
  • Platelet Glycoprotein 2b 3a Deficiency
  • Platelet Glycoprotein IIb IIIa Deficiency
  • Thrombasthenia, Glanzmann
  • Thrombasthenias

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1991(1986); use BLOOD PLATELET DISORDERS 1986-1990

MeSH Record

Previous Indexing

  • Blood Platelet Disorders (1967-1985)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Thrombasthenia. Medical Subject Headings (MeSH). 2026. Unique ID D013915. http://id.nlm.nih.gov/mesh/2026/D013915
  2. Thrombasthenia. In: Wikipedia. https://en.wikipedia.org/wiki/Glanzmann%27s_thrombasthenia
  3. Thrombasthenia. In: Wikidata. https://www.wikidata.org/wiki/Q1529258