Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Thrombin Time

Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.

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Classification

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Synonyms

7 entry terms
  • Reptilase Time
  • Reptilase Times
  • Thrombin Times
  • Time, Reptilase
  • Time, Thrombin
  • Times, Reptilase
  • Times, Thrombin

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Aspects Covered

14 allowable subheadings

Indexed with the subheadings adverse effects, classification, economics, ethics, history, instrumentation, methods, mortality, nursing, psychology, standards, statistics & numerical data, trends, veterinary.

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Indexing Annotation

usually NIM

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History Note

91(80); was see under BLOOD COAGULATION TESTS 1980-90

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Previous Indexing

  • Blood Coagulation Tests (1966-1979)
  • Fibrinogen (1966-1979)
  • Thrombin (1966-1979)

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References

  1. National Library of Medicine. Thrombin Time. Medical Subject Headings (MeSH). 2026. Unique ID D013918. http://id.nlm.nih.gov/mesh/2026/D013918
  2. Thrombin Time. In: Wikipedia. https://en.wikipedia.org/wiki/Thrombin_time
  3. Thrombin Time. In: Wikidata. https://www.wikidata.org/wiki/Q2520736