Chemicals and Drugs

Thymalfasin

A thymus hormone polypeptide found in thymosin fraction 5 (a crude thymus gland extract) but now produced by synthesis. It is used alone or with interferon as an immunomodulator for the treatment of CHRONIC HEPATITIS B and HEPATITIS C. Thymalfasin is also used for the treatment of chemotherapy-induced immunosuppression, and to enhance the efficacy of influenza and hepatitis B vaccines in immunocompromised patients.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thymus hormone polypeptide found in thymosin fraction 5 (a crude thymus gland extract) but now produced by synthesis. It is used alone or with interferon as an immunomodulator for the treatment of CHRONIC HEPATITIS B and HEPATITIS C. Thymalfasin is also used for the treatment of chemotherapy-induced immunosuppression, and to enhance the efficacy of influenza and hepatitis B vaccines in immunocompromised patients.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Thymosin alpha(1)
  • Thymosin alpha1
  • alpha1-Thymosin
  • alpha1 Thymosin
  • Zadaxin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1980)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Thymalfasin. Medical Subject Headings (MeSH). 2026. Unique ID D000077596. http://id.nlm.nih.gov/mesh/2026/D000077596
  2. Thymalfasin. In: Wikidata. https://www.wikidata.org/wiki/Q20817234