Chemicals and Drugs

Thyroid Hormone Receptors alpha

High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

31 entry terms
  • ERBA1 Gene Products
  • NR1A1 Gene Products
  • Proto-Oncogene Proteins c-erbA
  • Receptors alpha, Thyroid Hormone
  • THRA Gene Products
  • c-erb A Protein
  • c-erb A Proteins
  • c-erbA Protein
  • c-erbA Proteins
  • c-erbA alpha
  • c-erbA alpha Protein
  • c-erbA-1 Protein
  • erbA Proto-Oncogene Products
  • Gene Products, ERBA1
  • Gene Products, NR1A1
  • Gene Products, THRA
  • Proto Oncogene Proteins c erbA
  • Proto-Oncogene Products, erbA
  • c erb A Protein
  • c erb A Proteins
  • c erbA 1 Protein
  • c erbA Protein
  • c erbA Proteins
  • c erbA alpha
  • c erbA alpha Protein
  • c-erbA, Proto-Oncogene Proteins
  • erbA Proto Oncogene Products
  • Thyroid Hormone Receptor alpha-1
  • Thyroid Hormone Receptor alpha-2
  • Thyroid Hormone Receptor alpha 1
  • Thyroid Hormone Receptor alpha 2

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2003; use RECEPTORS, THYROID HORMONE 1994-2002

MeSH Record

Previous Indexing

  • Receptors, Thyroid Hormone (1988-2002)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.624.664.700.830w.500
  2. D12.776w.826w.850w.500

AMA Style

References

  1. National Library of Medicine. Thyroid Hormone Receptors alpha. Medical Subject Headings (MeSH). 2026. Unique ID D037021. http://id.nlm.nih.gov/mesh/2026/D037021
  2. Thyroid Hormone Receptors alpha. In: Wikidata. https://www.wikidata.org/wiki/Q7799751