Structured Summary
Abstract
A highly purified recombinant glycoprotein form of human THYROID-STIMULATING HORMONE, produced by recombinant DNA technology comprising two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites, and a beta subunit of 118 residues containing one N-linked glycosylation site. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.
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Classification
Broader headings
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MeSH Record
Synonyms
6 entry terms
- Recombinant Human TSH
- rhTSH
- Alfa, Thyrotropin
- Human TSH, Recombinant
- TSH, Recombinant Human
- Thyrogen
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2010
MeSH Record
Previous Indexing
- Glycoprotein Hormones, alpha Subunit (1991-2009)
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AMA Style
References
- National Library of Medicine. Thyrotropin Alfa. Medical Subject Headings (MeSH). 2026. Unique ID D057073. http://id.nlm.nih.gov/mesh/2026/D057073
- Thyrotropin Alfa. In: Wikidata. https://www.wikidata.org/wiki/Q20816877