Chemicals and Drugs

Timolol Maleate Drug Combination Brimonidine Tartrate

A pharmaceutical preparation of brimonidine tartrate and timolol maleate. The combined ADRENERGIC ALPHA2 RECEPTOR AGONIST and ADRENERGIC BETA-ANTAGONIST activity of these drugs reduce INTRAOCULAR PRESSURE in GLAUCOMA patients.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A pharmaceutical preparation of brimonidine tartrate and timolol maleate. The combined ADRENERGIC ALPHA2 RECEPTOR AGONIST and ADRENERGIC BETA-ANTAGONIST activity of these drugs reduce INTRAOCULAR PRESSURE in GLAUCOMA patients.

Chemical Identity

Chemical Information

Molecular Formula
C24H34BrN9O3S
Molecular Weight
608.6 g/mol
CAS Registry No.
952743-07-6
IUPAC Name
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine;(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
InChIKey
ZUIFJYRNWWNOPB-PPHPATTJSA-N
SMILES
CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O.C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br
MeSH Unique ID
D000068599
Source
PubChem CID 11387895

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Brimonidine Tartrate, Timolol Maleate Drug Combination
  • Brimonidine Tartrate-Timolol Maleate
  • Brimonidine Tartrate-Timolol Maleate Drug Combination
  • Brimonidine Tartrate Timolol Maleate
  • Brimonidine Tartrate Timolol Maleate Drug Combination
  • Maleate, Brimonidine Tartrate-Timolol
  • Tartrate-Timolol Maleate, Brimonidine
  • Combigan

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (2011)

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.624w.915w.500w
  2. D02w.033w.755.624w.915w.500w
  3. D02w.092w.063w.624w.915w.500w
  4. D02w.886w.675.867w.768w.500w
  5. D03w.383.129w.708.867w.768w.500w
  6. D03w.633.100.857.070.500w
  7. D26.310w.312w

AMA Style

References

  1. National Library of Medicine. Timolol Maleate Drug Combination Brimonidine Tartrate. Medical Subject Headings (MeSH). 2026. Unique ID D000068599. http://id.nlm.nih.gov/mesh/2026/D000068599
  2. Timolol Maleate Drug Combination Brimonidine Tartrate. In: Wikipedia. https://en.wikipedia.org/wiki/Brimonidine/timolol
  3. Timolol Maleate Drug Combination Brimonidine Tartrate. In: Wikidata. https://www.wikidata.org/wiki/Q4968132
  4. Timolol Maleate Drug Combination Brimonidine Tartrate. In: PubChem Compound. CID 11387895. https://pubchem.ncbi.nlm.nih.gov/compound/11387895