Structured Summary
Abstract
Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors.
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Classification
Broader headings
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Synonyms
5 entry terms
- Nucleases, Transcription Activator-Like Effector
- TALEN
- TALENs
- Nucleases, Transcription Activator Like Effector
- Transcription Activator Like Effector Nucleases
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Transcription Activator-Like Effector Nucleases. Medical Subject Headings (MeSH). 2026. Unique ID D000069896. http://id.nlm.nih.gov/mesh/2026/D000069896
- Transcription Activator-Like Effector Nucleases. In: Wikipedia. https://en.wikipedia.org/wiki/Transcription_activator-like_effector_nuclease
- Transcription Activator-Like Effector Nucleases. In: Wikidata. https://www.wikidata.org/wiki/Q7833921