Chemicals and Drugs

Transcription Activator-Like Effectors

Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.

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Broader headings

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MeSH Record

Synonyms

10 entry terms
  • TAL Effector
  • TAL Effectors
  • Transcription Activator-Like Effector
  • Activator-Like Effector, Transcription
  • Effector, TAL
  • Effector, Transcription Activator-Like
  • Effectors, TAL
  • Effectors, Transcription Activator-Like
  • Transcription Activator Like Effector
  • Transcription Activator Like Effectors

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Hierarchy

Tree Numbers

  1. D12.776w.097.890w
  2. D12.776w.260w.755.700w
  3. D12.776w.930w.900.550w
  4. D23.946w.896w.490w

AMA Style

References

  1. National Library of Medicine. Transcription Activator-Like Effectors. Medical Subject Headings (MeSH). 2026. Unique ID D000071336. http://id.nlm.nih.gov/mesh/2026/D000071336
  2. Transcription Activator-Like Effectors. In: Wikipedia. https://en.wikipedia.org/wiki/Transcription_activator-like_effector
  3. Transcription Activator-Like Effectors. In: Wikidata. https://www.wikidata.org/wiki/Q7669289