Chemicals and Drugs

Transcription Factor AP-2

A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

47 entry terms
  • AP-2 Enhancer Binding Protein
  • Activator Protein AP-2
  • Enhancer-Binding Protein AP-2
  • Transcription Factor AP2
  • AP 2 Enhancer Binding Protein
  • AP-2, Activator Protein
  • AP-2, Enhancer-Binding Protein
  • AP-2, Transcription Factor
  • Activator Protein AP 2
  • Enhancer Binding Protein AP 2
  • Transcription Factor AP 2
  • AP-2 alpha Protein
  • AP-2 beta Protein
  • AP-2 epsilon Protein
  • AP-2 gamma Protein
  • AP-2delta Protein
  • TFAP2B Protein
  • TFAP2alpha Protein
  • Transcription Factor AP-2 alpha Protein
  • Transcription Factor AP-2 beta Protein
  • Transcription Factor AP-2 delta Protein
  • Transcription Factor AP-2 epsilon Protein
  • Transcription Factor AP-2 gamma Protein
  • Transcription Factor AP-2alpha
  • Transcription Factor AP-2beta
  • Transcription Factor AP-2epsilon
  • Transcription Factor AP-2gamma
  • Transcription Factor Ap-2delta
  • AP 2 alpha Protein
  • AP 2 beta Protein
  • AP 2 gamma Protein
  • AP 2delta Protein
  • AP-2alpha, Transcription Factor
  • AP-2beta, Transcription Factor
  • AP-2epsilon, Transcription Factor
  • AP-2gamma, Transcription Factor
  • Ap-2delta, Transcription Factor
  • Transcription Factor AP 2 alpha Protein
  • Transcription Factor AP 2 beta Protein
  • Transcription Factor AP 2 delta Protein
  • Transcription Factor AP 2 epsilon Protein
  • Transcription Factor AP 2 gamma Protein
  • Transcription Factor AP 2alpha
  • Transcription Factor AP 2beta
  • Transcription Factor AP 2epsilon
  • Transcription Factor AP 2gamma
  • Transcription Factor Ap 2delta

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

see SCR for organism-specific terms

MeSH Record

History Note

2006(1987)

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1987-2005)
  • Transcription Factors (1987-2005)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.760w
  2. D12.776w.930w.907w

AMA Style

References

  1. National Library of Medicine. Transcription Factor AP-2. Medical Subject Headings (MeSH). 2026. Unique ID D050656. http://id.nlm.nih.gov/mesh/2026/D050656
  2. Transcription Factor AP-2. In: Wikipedia. https://en.wikipedia.org/wiki/Activating_protein_2
  3. Transcription Factor AP-2. In: Wikidata. https://www.wikidata.org/wiki/Q24725104