Structured Summary
Abstract
Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.
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Synonyms
5 entry terms
- Transforming Growth Factor
- Factor, Transforming Growth
- Factors, Transforming Growth
- Growth Factor, Transforming
- Growth Factors, Transforming
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
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Indexing Annotation
general or unspecified; prefer specifics
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History Note
89
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Previous Indexing
- Growth Substances (1966-1988)
- Peptides (1966-1988)
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NLM Classification
QU 107
AMA Style
References
- National Library of Medicine. Transforming Growth Factors. Medical Subject Headings (MeSH). 2026. Unique ID D015291. http://id.nlm.nih.gov/mesh/2026/D015291
- Transforming Growth Factors. In: Wikipedia. https://en.wikipedia.org/wiki/Transforming_growth_factor
- Transforming Growth Factors. In: Wikidata. https://www.wikidata.org/wiki/Q423671