Chemicals and Drugs

Translationally-Controlled 1 Tumor Protein

A highly expressed protein in tumor cells, encoded by Tpt1 gene. It's involved in various cellular activities including protein synthesis, calcium-binding, MICROTUBULE stabilization, growth, and cell survival. Also, Tpt1 identified as a direct target gene of P53 tumor suppression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A highly expressed protein in tumor cells, encoded by Tpt1 gene. It's involved in various cellular activities including protein synthesis, calcium-binding, MICROTUBULE stabilization, growth, and cell survival. Also, Tpt1 identified as a direct target gene of P53 tumor suppression.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

14 entry terms
  • Histamine Releasing Factor
  • Histamine Releasing Factor, Lymphocyte-Dependent
  • Histamine-Releasing Factor (IgE-Dependent)
  • Protein P23, Ehrlich Ascites Tumor
  • TPT1 Protein
  • Translationally-Controlled Tumor Protein
  • Tumor Protein, Translationally-Controlled 1
  • Factor, Histamine Releasing
  • Histamine Releasing Factor, Lymphocyte Dependent
  • Protein, TPT1
  • Protein, Translationally-Controlled Tumor
  • Translationally Controlled Tumor Protein
  • Tumor Protein, Translationally Controlled 1
  • Tumor Protein, Translationally-Controlled

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2022 (1985)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.963w
  2. D12.776w.476.941w
  3. D12.776w.624.720w

AMA Style

References

  1. National Library of Medicine. Translationally-Controlled 1 Tumor Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000090324. http://id.nlm.nih.gov/mesh/2026/D000090324
  2. Translationally-Controlled 1 Tumor Protein. In: Wikipedia. https://en.wikipedia.org/wiki/Translationally_controlled_tumour_protein
  3. Translationally-Controlled 1 Tumor Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24775511