Structured Summary
Abstract
A cloprostenol derivative that is used as an ANTIHYPERTENSIVE AGENT in the treatment of OPEN-ANGLE GLAUCOMA and OCULAR HYPERTENSION.
Chemical Identity
Chemical Information
- Molecular Formula
- C26H35F3O6
- Molecular Weight
- 500.5 g/mol
- CAS Registry No.
- 157283-68-6
- IUPAC Name
- propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate
- InChIKey
- MKPLKVHSHYCHOC-AHTXBMBWSA-N
- SMILES
- CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](COC2=CC=CC(=C2)C(F)(F)F)O)O)O
- MeSH Unique ID
- D000069557
- Source
- PubChem CID 5282226
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- (((1R)-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-5-heptenoic acid, 1-methylethyl ester
- AL-6221
- AL6221
- Travatan
- Travatan Z
- AL 6221
- Z, Travatan
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2016 (2001)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Travoprost. Medical Subject Headings (MeSH). 2026. Unique ID D000069557. http://id.nlm.nih.gov/mesh/2026/D000069557
- Travoprost. In: Wikipedia. https://en.wikipedia.org/wiki/Travoprost
- Travoprost. In: Wikidata. https://www.wikidata.org/wiki/Q2193376
- Travoprost. In: PubChem Compound. CID 5282226. https://pubchem.ncbi.nlm.nih.gov/compound/5282226