Chemicals and Drugs

Trihexosylceramides

Glycosphingolipids which contain as their polar head group a trisaccharide (galactose-galactose-glucose) moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in ceramide trihexosidase, is the cause of angiokeratoma corporis diffusum (FABRY DISEASE).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Glycosphingolipids which contain as their polar head group a trisaccharide (galactose-galactose-glucose) moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in ceramide trihexosidase, is the cause of angiokeratoma corporis diffusum (FABRY DISEASE).

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • Ceramide Trihexosides
  • Trihexosyl Ceramides
  • Ceramides, Trihexosyl
  • Trihexosides, Ceramide

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

91(79); was see under GLYCOSPHINGOLIPIDS 1979-90

MeSH Record

Previous Indexing

  • Ceramides (1972-1978)
  • Cerebrosides (1966-1978)
  • Glycosphingolipids (1975-1978)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Trihexosylceramides. Medical Subject Headings (MeSH). 2026. Unique ID D014281. http://id.nlm.nih.gov/mesh/2026/D014281
  2. Trihexosylceramides. In: Wikidata. https://www.wikidata.org/wiki/Q76544414