Chemicals and Drugs

Triparanol

Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.

Chemical Identity

Chemical Information

Molecular Formula
C27H32ClNO2
Molecular Weight
438.0 g/mol
CAS Registry No.
78-41-1
IUPAC Name
2-(4-chlorophenyl)-1-[4-[2-(diethylamino)ethoxy]phenyl]-1-(4-methylphenyl)ethanol
InChIKey
SYHDSBBKRLVLFF-UHFFFAOYSA-N
SMILES
CCN(CC)CCOC1=CC=C(C=C1)C(CC2=CC=C(C=C2)Cl)(C3=CC=C(C=C3)C)O
MeSH Unique ID
D014308
Source
PubChem CID 6536

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • MER-29
  • Metasqualene
  • MER 29
  • MER29

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

64(63)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Triparanol. Medical Subject Headings (MeSH). 2026. Unique ID D014308. http://id.nlm.nih.gov/mesh/2026/D014308
  2. Triparanol. In: Wikipedia. https://en.wikipedia.org/wiki/Triparanol
  3. Triparanol. In: Wikidata. https://www.wikidata.org/wiki/Q5988254
  4. Triparanol. In: PubChem Compound. CID 6536. https://pubchem.ncbi.nlm.nih.gov/compound/6536