Structured Summary
Abstract
A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE with D-tryptophan substitution at residue 6.
Chemical Identity
Chemical Information
- Molecular Formula
- C64H82N18O13
- Molecular Weight
- 1311.4 g/mol
- CAS Registry No.
- 57773-63-4
- IUPAC Name
- (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
- InChIKey
- VXKHXGOKWPXYNA-PGBVPBMZSA-N
- SMILES
- CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8
- MeSH Unique ID
- D017329
- Source
- PubChem CID 25074470
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
24 entry terms
- Pamoate, Triptorelin
- 6-D-Tryptophan-Luteinizing Hormone-Releasing Factor (Pig)
- AY-25650
- CL-118532
- D-Trp-6-LH-RH
- Decapeptyl
- Decapeptyl Depot
- Decapeptyl LP
- Decapeptyl Trimestral
- GnRH, Trp(6)-
- LHRH, Trp(6)-
- LHRH, Tryptophyl(6)-
- Trelstar
- Triptorelin
- Triptorelin Embonate
- Wy-42462
- AY 25650
- AY25650
- CL 118532
- CL118532
- Embonate, Triptorelin
- Trimestral, Decapeptyl
- Wy 42462
- Wy42462
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1993; use TRIPTORELIN (NM) 1980-1992; for LHRH, TRP(6)- use TRIPTORELIN (NM) 1995-1999
MeSH Record
Previous Indexing
- Gonadorelin/analogs & derivatives (1978-1992)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Triptorelin Pamoate. Medical Subject Headings (MeSH). 2026. Unique ID D017329. http://id.nlm.nih.gov/mesh/2026/D017329
- Triptorelin Pamoate. In: Wikipedia. https://en.wikipedia.org/wiki/Triptorelin
- Triptorelin Pamoate. In: Wikidata. https://www.wikidata.org/wiki/Q1992452
- Triptorelin Pamoate. In: PubChem Compound. CID 25074470. https://pubchem.ncbi.nlm.nih.gov/compound/25074470