Chemicals and Drugs

Trypanosoma Variant Surface Glycoproteins

Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • SSP-4
  • Surface Variant Glycoproteins, Trypanosoma
  • Trypanosoma Variant Surface Coat Glycoproteins
  • Variant Surface Glycoproteins, Trypanosoma
  • VSG 117
  • VSG 118
  • VSG 221

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

88

MeSH Record

Previous Indexing

  • Glycoproteins (1966-1987)
  • Membrane Proteins (1977-1987)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.990w
  2. D12.776w.395w.550w.990w
  3. D12.776w.543w.550w.990w
  4. D12.776w.820.125.900w
  5. D23.050w.293.900w
  6. D23.050w.301.900w

AMA Style

References

  1. National Library of Medicine. Trypanosoma Variant Surface Glycoproteins. Medical Subject Headings (MeSH). 2026. Unique ID D014643. http://id.nlm.nih.gov/mesh/2026/D014643
  2. Trypanosoma Variant Surface Glycoproteins. In: Wikipedia. https://en.wikipedia.org/wiki/Variant_surface_glycoprotein
  3. Trypanosoma Variant Surface Glycoproteins. In: Wikidata. https://www.wikidata.org/wiki/Q2510707