Chemicals and Drugs

Tryptophan Synthase

An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20.

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Classification

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Synonyms

3 entry terms
  • Tryptophan Synthetase
  • Synthase, Tryptophan
  • Synthetase, Tryptophan

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

80; was TRYPTOPHAN SYNTHETASE 1972-79 (Prov 1972-73)

MeSH Record

Previous Indexing

  • Hydro-Lyases (1966-1971)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Tryptophan Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D014367. http://id.nlm.nih.gov/mesh/2026/D014367
  2. Tryptophan Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Tryptophan_synthase
  3. Tryptophan Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q2307998