Structured Summary
Abstract
An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1.
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Classification
Broader headings
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MeSH Record
Synonyms
3 entry terms
- Tryptophan Indole-Lyase
- Indole-Lyase, Tryptophan
- Tryptophan Indole Lyase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
91(72); was see under LYASES 1972-90
MeSH Record
Previous Indexing
- Hydro-Lyases (1966-1971)
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AMA Style
References
- National Library of Medicine. Tryptophanase. Medical Subject Headings (MeSH). 2026. Unique ID D014368. http://id.nlm.nih.gov/mesh/2026/D014368
- Tryptophanase. In: Wikipedia. https://en.wikipedia.org/wiki/Tryptophanase
- Tryptophanase. In: Wikidata. https://www.wikidata.org/wiki/Q7848809