Structured Summary
Abstract
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
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Classification
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Synonyms
8 entry terms
- Cellular Tumor Antigen p53
- Oncoprotein p53
- TP53 Protein
- TRP53 Protein
- p53 Antigen
- p53 Tumor Suppressor Protein
- pp53 Phosphoprotein
- Phosphoprotein, pp53
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2005(1991);
MeSH Record
Previous Indexing
- Neoplasm Proteins (1981-1989)
- Oncogene Products (1990)
- Phosphoproteins (1981-1990)
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AMA Style
References
- National Library of Medicine. Tumor Suppressor Protein p53. Medical Subject Headings (MeSH). 2026. Unique ID D016159. http://id.nlm.nih.gov/mesh/2026/D016159
- Tumor Suppressor Protein p53. In: Wikipedia. https://en.wikipedia.org/wiki/P53
- Tumor Suppressor Protein p53. In: Wikidata. https://www.wikidata.org/wiki/Q283350