Chemicals and Drugs

Type 5 Cyclic Nucleotide Phosphodiesterases

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.

MeSH Record

Classification

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MeSH Record

Synonyms

15 entry terms
  • Cyclic Nucleotide Phosphodiesterases, Type 5
  • PDE5 Phosphodiesterases
  • Phosphodiesterase 5
  • Phosphodiesterase 5A
  • Phosphodiesterase 5A, cGMP-Specific
  • Phosphodiesterase Type 5
  • Phosphodiesterase Type V
  • Phosphodiesterase V
  • Phosphodiesterase-5
  • cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase
  • Phosphodiesterase 5A, cGMP Specific
  • Phosphodiesterases, PDE5
  • Type 5, Phosphodiesterase
  • Type V, Phosphodiesterase
  • cGMP-Specific Phosphodiesterase 5A

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1998)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Type 5 Cyclic Nucleotide Phosphodiesterases. Medical Subject Headings (MeSH). 2026. Unique ID D054706. http://id.nlm.nih.gov/mesh/2026/D054706
  2. Type 5 Cyclic Nucleotide Phosphodiesterases. In: Wikidata. https://www.wikidata.org/wiki/Q77185187