Phenomena and Processes

Unstable DNA Sequence

A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.

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Synonyms

5 entry terms
  • DNA Sequence, Unstable
  • Unstable DNA Sequences
  • DNA Sequences, Unstable
  • Sequence, Unstable DNA
  • Sequences, Unstable DNA

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2004 (1998); use TRINUCLEOTIDE REPEAT EXPANSION 1998-2003

MeSH Hierarchy

Tree Number

  1. G05.360w.340w.024.189w

AMA Style

References

  1. National Library of Medicine. Unstable DNA Sequence. Medical Subject Headings (MeSH). 2026. Unique ID D043243. http://id.nlm.nih.gov/mesh/2026/D043243
  2. Unstable DNA Sequence. In: Wikipedia. https://en.wikipedia.org/wiki/Unstable_DNA_sequence
  3. Unstable DNA Sequence. In: Wikidata. https://www.wikidata.org/wiki/Q70684983