Chemicals and Drugs

Uridine Diphosphate Glucuronic Acid

A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones.

Chemical Identity

Chemical Information

Molecular Formula
C15H22N2O18P2
Molecular Weight
580.28 g/mol
CAS Registry No.
2616-64-0
IUPAC Name
(2S,3S,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
InChIKey
HDYANYHVCAPMJV-LXQIFKJMSA-N
SMILES
C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)O)O
MeSH Unique ID
D014535
Source
PubChem CID 17473

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • UDP Glucuronic Acid
  • UDPGA
  • Uridine Diphosphoglucuronic Acid
  • Acid, UDP Glucuronic
  • Acid, Uridine Diphosphoglucuronic
  • Diphosphoglucuronic Acid, Uridine
  • Glucuronic Acid, UDP

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under URIDINE DIPHOSPHATE SUGARS 1975-90

MeSH Record

Previous Indexing

  • Glucuronates (1973-1974)
  • Uridine Diphosphate Sugars (1973-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.742.686.850.600w.677.375w
  2. D09w.408w.620w.569.727.375w
  3. D13.695w.740.850.600w.677.375w
  4. D13.695w.827w.708.727.375w
  5. D13.695w.827w.919.600w.677.375w

AMA Style

References

  1. National Library of Medicine. Uridine Diphosphate Glucuronic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D014535. http://id.nlm.nih.gov/mesh/2026/D014535
  2. Uridine Diphosphate Glucuronic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Uridine_diphosphate_glucuronic_acid
  3. Uridine Diphosphate Glucuronic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q277638
  4. Uridine Diphosphate Glucuronic Acid. In: PubChem Compound. CID 17473. https://pubchem.ncbi.nlm.nih.gov/compound/17473