Structured Summary
Abstract
Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.
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Classification
Broader headings
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Synonyms
9 entry terms
- Ucn II
- Ucn III
- Urocortin
- Urocortin 1
- Urocortin 2
- Urocortin 3
- Urocortin I
- Urocortin II
- Urocortin III
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2008 (1995)
MeSH Record
Previous Indexing
- Corticotropin-Releasing Hormone (1995-2007)
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AMA Style
References
- National Library of Medicine. Urocortins. Medical Subject Headings (MeSH). 2026. Unique ID D054832. http://id.nlm.nih.gov/mesh/2026/D054832
- Urocortins. In: Wikidata. https://www.wikidata.org/wiki/Q76853559