Chemicals and Drugs

Ursodeoxycholic Acid

An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.

Chemical Identity

Chemical Information

Molecular Formula
C24H40O4
Molecular Weight
392.6 g/mol
CAS Registry No.
128-13-2
IUPAC Name
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
InChIKey
RUDATBOHQWOJDD-UZVSRGJWSA-N
SMILES
C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
MeSH Unique ID
D014580
Source
PubChem CID 31401

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

23 entry terms
  • 3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid
  • Deoxyursocholic Acid
  • Ursacholic Acid
  • Ursodiol
  • 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid
  • Acid, Deoxyursocholic
  • Acid, Ursacholic
  • Acid, Ursodeoxycholic
  • Cholit-Ursan
  • Cholofalk
  • Delursan
  • Destolit
  • Sodium Ursodeoxycholate
  • Urdox
  • Urso
  • Urso Heumann
  • Ursobilane
  • Ursochol
  • Ursofalk
  • Ursogal
  • Ursolite
  • Ursolvan
  • Ursodeoxycholate, Sodium

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /defic /physiol permitted; urso- refers to its first isol from URSIDAE (Latin ursus)

MeSH Record

History Note

91(80); was see under DEOXYCHOLIC ACID 1980-90

MeSH Record

Previous Indexing

  • Bile Acids and Salts (1966-1972)
  • Chenodeoxycholic Acid (1973-1979)
  • Deoxycholic Acid (1973-1974) /analogs & derivatives (1975-1979)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Ursodeoxycholic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D014580. http://id.nlm.nih.gov/mesh/2026/D014580
  2. Ursodeoxycholic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Ursodeoxycholic_acid
  3. Ursodeoxycholic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q241374
  4. Ursodeoxycholic Acid. In: PubChem Compound. CID 31401. https://pubchem.ncbi.nlm.nih.gov/compound/31401