Chemicals and Drugs

Vasopeptidase Inhibitors

A class of cardiovascular drugs indicated for hypertension and congestive heart failure that simultaneously inhibit both NEUTRAL ENDOPEPTIDASE and ANGIOTENSIN CONVERTING ENZYME. They increase the availability of NATRIURETIC PEPTIDES and BRADYKININ and inhibit production of ANGIOTENSIN II.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of cardiovascular drugs indicated for hypertension and congestive heart failure that simultaneously inhibit both NEUTRAL ENDOPEPTIDASE and ANGIOTENSIN CONVERTING ENZYME. They increase the availability of NATRIURETIC PEPTIDES and BRADYKININ and inhibit production of ANGIOTENSIN II.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • ACE-NEP Inhibitors
  • NEP-ACE Inhibitors
  • Vasopeptidase Inhibitor
  • ACE NEP Inhibitors
  • Inhibitor, Vasopeptidase
  • NEP ACE Inhibitors

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Angiotensin-Converting Enzyme Inhibitors (1999-2017)
  • Neprilysin/antagonists and inhibitors (1999-2017)

MeSH Hierarchy

Tree Number

  1. D27.505.519w.389w.745w.085w.500

AMA Style

References

  1. National Library of Medicine. Vasopeptidase Inhibitors. Medical Subject Headings (MeSH). 2026. Unique ID D000075563. http://id.nlm.nih.gov/mesh/2026/D000075563
  2. Vasopeptidase Inhibitors. In: Wikidata. https://www.wikidata.org/wiki/Q50429631