Structured Summary
Abstract
Alkaloids with powerful hypotensive effects isolated from American or European Hellebore (Veratrum viride Ait. Liliaceae and Veratrum album L. Liliaceae). They increase cholinergic and decrease adrenergic tone with appropriate side effects and at higher doses depress respiration and produce cardiac arrhythmias; only the ester alkaloids have been used as hypotensive agents in specific instances. They have been generally replaced by drugs with fewer adverse effects.
MeSH Record
Classification
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Alkaloids, Veratrum
MeSH Record
Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
antihypertensives
MeSH Record
History Note
75
MeSH Record
Previous Indexing
- Veratrum (1966-1974)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QV 151
AMA Style
References
- National Library of Medicine. Veratrum Alkaloids. Medical Subject Headings (MeSH). 2026. Unique ID D014704. http://id.nlm.nih.gov/mesh/2026/D014704
- Veratrum Alkaloids. In: Wikidata. https://www.wikidata.org/wiki/Q75011817