Chemicals and Drugs

Vigabatrin

An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID and is used as an anticonvulsant. (From Martindale The Extra Pharmacopoeia, 31st ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID and is used as an anticonvulsant. (From Martindale The Extra Pharmacopoeia, 31st ed)

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • gamma-Vinyl-GABA
  • gamma-Vinyl-gamma-Aminobutyric Acid
  • gamma Vinyl GABA
  • gamma Vinyl gamma Aminobutyric Acid
  • Sabril
  • Sabrilex

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2000; use VIGABATRIN 1977-1999

MeSH Record

Previous Indexing

  • Aminocaproic Acids (1981-1994)
  • GABA/analogs & derivatives (1979-1980)
  • GABA/analogs & derivatives (1994-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Vigabatrin. Medical Subject Headings (MeSH). 2026. Unique ID D020888. http://id.nlm.nih.gov/mesh/2026/D020888
  2. Vigabatrin. In: Wikipedia. https://en.wikipedia.org/wiki/Vigabatrin
  3. Vigabatrin. In: Wikidata. https://www.wikidata.org/wiki/Q421663