Chemicals and Drugs

Vinca Alkaloids

A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Alkaloids, Vinca

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73

MeSH Record

Previous Indexing

  • Alkaloids (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.436w.681.827w
  2. D03w.633.100.473.402w.681.827w
  3. D03w.633.100.496.500.500w.681.827w

MeSH Record

NLM Classification

QV 269

AMA Style

References

  1. National Library of Medicine. Vinca Alkaloids. Medical Subject Headings (MeSH). 2026. Unique ID D014748. http://id.nlm.nih.gov/mesh/2026/D014748
  2. Vinca Alkaloids. In: Wikipedia. https://en.wikipedia.org/wiki/Vinca_alkaloid
  3. Vinca Alkaloids. In: Wikidata. https://www.wikidata.org/wiki/Q3559405